Description

5-Methylpyridine-3-Sulfonyl Chloride is a versatile and reactive sulfonyl chloride derivative used as a key building block in organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, introducing the sulfonyl functional group into target molecules to modify their properties. This compound is particularly essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its sulfonyl moiety.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a labeling or modifying reagent for proteins and other biomolecules due to its reactivity with amines and alcohols.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of sulfonated dyes and colorants.
• Ligand & Catalyst Development: Used to synthesize novel ligands for metal complexes and organocatalysts.

Basic Information

Product Name	5-Methylpyridine-3-Sulfonyl Chloride
CAS No.	166337-57-1
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 5-methyl-; 5-Methyl-3-pyridinesulfonyl chloride; 5-Methylpyridine-3-sulphonyl chloride; 3-(Chlorosulfonyl)-5-methylpyridine; 5-Methylnicotinic acid sulfonyl chloride; 5-Methyl-3-pyridylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Methylpyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.