Description

2-Methoxy-4-(Trifluoromethyloxy)Phenol is a specialized phenolic compound featuring a methoxy and a trifluoromethoxy substituent on the aromatic ring. This unique structure makes it a valuable advanced intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development teams working on active pharmaceutical ingredients (APIs), crop protection agents, and high-performance materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group can improve activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a functional monomer or additive to introduce specific properties like hydrophobicity or chemical resistance into specialty polymers.
• Chemical Research (R&D): Employed in academic and industrial laboratories for method development and exploring new chemical entities in medicinal and synthetic chemistry.

Basic Information

Product Name	2-Methoxy-4-(Trifluoromethyloxy)Phenol
CAS No.	166312-49-8
Molecular Formula	C8H7F3O3
Molecular Weight	208.14 g/mol
Synonyms	4-Hydroxy-3-methoxy-α,α,α-trifluoroanisole; 2-Methoxy-4-(trifluoromethoxy)phenol; 4-(Trifluoromethoxy)guaiacol; Guaiacol, 4-(trifluoromethoxy)-; Phenol, 2-methoxy-4-(trifluoromethoxy)-; 1-Hydroxy-2-methoxy-4-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(Trifluoromethyloxy)Phenol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.