Description

4-Chloro-(3-Pyrazolyl)-6-Methyl Pyrimidine CAS NO 166197-06-4 is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Research: Versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Material Science: Potential monomer or functional component in the development of specialty polymers and advanced materials.
• Contract Manufacturing: Supplied to CDMOs for use in custom synthesis and scale-up projects under cGMP guidelines.

Basic Information

Product Name	4-Chloro-(3-Pyrazolyl)-6-Methyl Pyrimidine
CAS No.	166197-06-4
Molecular Formula	C8H7ClN4
Molecular Weight	194.62 g/mol
Synonyms	4-Chloro-6-methyl-2-(1H-pyrazol-3-yl)pyrimidine; 6-Methyl-4-chloro-2-(1H-pyrazol-3-yl)pyrimidine; 2-(1H-Pyrazol-3-yl)-4-chloro-6-methylpyrimidine; 4-Chloro-6-methyl-2-(1H-pyrazol-3-yl)pyrimidine; 166197-06-4; 4-Chloro-6-methyl-2-(1H-pyrazol-5-yl)pyrimidine (tautomer); Pyrimidine, 4-chloro-6-methyl-2-(1H-pyrazol-3-yl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-(3-Pyrazolyl)-6-Methyl Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.