Description

2-Naphthalenecarboxamide, N-(6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)- is a specialized heterocyclic compound that serves as a high-value synthetic intermediate. Its molecular architecture, combining naphthalene and a substituted pyrimidinedione moiety, makes it a critical building block for advanced chemical synthesis. This product is primarily sought by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for research into central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic core.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct fused polycyclic systems for material science and chemical biology applications.
• Biochemical Research: Potential ligand or scaffold in medicinal chemistry for probing protein-ligand interactions and structure-activity relationship (SAR) studies.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing specialized naphthalene-based dyes and colorants.

Basic Information

Product Name	2-Naphthalenecarboxamide, N-(6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-
CAS No.	166115-76-0
Molecular Formula	C₁₇H₁₈N₄O₃
Molecular Weight	326.35 g/mol
Synonyms	N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-2-naphthamide; 5-[(2-Naphthoylamino]-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione; 1,3-Dimethyl-5-[(2-naphthoylamino]barbituric Acid; 5-(2-Naphthamido)-1,3-dimethylbarbituric Acid; 166115-76-0; Aminophylline naphthamide derivative; Barbituric acid naphthamide derivative
EINECS	Contact for details

Quality Control

Our production of 2-Naphthalenecarboxamide, N-(6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)- adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.