Description

Orbofiban Acetate CAS NO 165800-05-5 is a high-purity, non-peptide glycoprotein IIb/IIIa receptor antagonist. This compound is a critical active pharmaceutical ingredient (API) and research chemical, valued for its potent antiplatelet activity. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions in the development and production of novel cardiovascular therapeutics targeting thrombosis.

Application

• Active Pharmaceutical Ingredient (API) in the synthesis of antiplatelet and antithrombotic medications.
• Pharmacological Research for studying platelet aggregation mechanisms and glycoprotein IIb/IIIa receptor function.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Preclinical Development of new cardiovascular drug candidates targeting arterial thrombosis.
• Biochemical Assay development for high-throughput screening of platelet inhibitors.

Basic Information

Product Name	Orbofiban Acetate
CAS No.	165800-05-5
Molecular Formula	C29H38N2O6 • C2H4O2
Molecular Weight	562.65 g/mol
Synonyms	Orbofiban acetate; SC-57099B; L-734,217; (2S)-2-[(4-{4-[amino(imino)methyl]phenyl}-1-piperidinyl)carbonyl]amino]-3-(4-methylphenyl)propanoic acid acetate; Ro 44-9883 acetate; Glycoprotein IIb/IIIa antagonist SC-57099B; Acetic acid, compound with (2S)-2-[[(4-[[amino(imino)methyl]phenyl]-1-piperidinyl)carbonyl]amino]-3-(4-methylphenyl)propanoic acid (1:1)
EINECS	Contact for details

Quality Control

Our Orbofiban Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure compliance with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) confirming identity, purity, and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.