Description

Terutroban is a potent and selective thromboxane-prostanoid (TP) receptor antagonist, a key compound in cardiovascular and thrombosis research. Its primary value lies in its ability to inhibit platelet aggregation and vasoconstriction, making it a critical tool for investigating novel therapeutic pathways. This high-purity compound is essential for pharmaceutical R&D, particularly for researchers and manufacturers developing next-generation antiplatelet and antithrombotic agents. Terutroban CAS NO 165538-40-9 is supplied to meet the stringent demands of preclinical and analytical applications.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel antiplatelet drugs.
• Cardiovascular Disease Studies: Used in preclinical research to investigate mechanisms for treating atherosclerosis, stroke, and other thrombotic disorders.
• Pharmacology & Mechanism of Action (MOA) Studies: Serves as a selective TP receptor antagonist to study thromboxane A2 signaling pathways in vitro and in vivo.
• Analytical Reference Standard: Employed as a high-purity calibrant in HPLC, LC-MS, and NMR for quality control and method development.
• Biochemical Assay Development: Utilized in screening assays to identify and evaluate new compounds targeting the TP receptor.

Basic Information

Product Name	Terutroban
CAS No.	165538-40-9
Molecular Formula	C23H22F3NO4
Molecular Weight	433.42 g/mol
Synonyms	S 18886; Terutroban sodium; 3-[(3R)-3-[[4-[(3-Fluorophenyl)methoxy]phenyl]sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid; S-18886; Terutrobanum; 3-[(3R)-3-[[4-[(3-Fluorophenyl)methoxy]phenyl]sulfonylamino]-1,2,3,4-tetrahydro-9H-carbazol-9-yl]propanoic acid
EINECS	Contact for details

Quality Control

Our Terutroban is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all specifications and test results to ensure compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.