Description

2-Pyrimidinamine,4,6-Difluoro-n-Methyl- is a fluorinated pyrimidine derivative, a high-value chemical intermediate prized for its role in constructing complex molecular architectures. Its core value lies in enabling the synthesis of advanced pharmaceutical compounds and agrochemicals, where its specific substitution pattern is critical for bioactivity. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its fluorinated pyrimidine core.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and novel compound library generation.
• Material Science Precursor: Potential use in the development of specialty polymers, liquid crystals, or organic electronic materials requiring specific heterocyclic components.

Basic Information

Product Name	2-Pyrimidinamine,4,6-Difluoro-n-Methyl-
CAS No.	165258-57-1
Molecular Formula	C5H5F2N3
Molecular Weight	145.11 g/mol
Synonyms	4,6-Difluoro-N-methylpyrimidin-2-amine; N-Methyl-4,6-difluoropyrimidin-2-amine; 2-Amino-4,6-difluoro-N-methylpyrimidine; 4,6-Difluoro-2-(methylamino)pyrimidine; 165258-57-1; 4,6-Difluoro-N-methyl-2-pyrimidinamine; 2-Pyrimidinamine, 4,6-difluoro-N-methyl-
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinamine,4,6-Difluoro-n-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.