Description

Fa-Cys(Farnesyl)-Oh is a specialized farnesylated cysteine derivative, a key building block in chemical synthesis and biochemical research. This compound is crucial for studying protein prenylation, a vital post-translational modification involved in cellular signaling and membrane association. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, cancer research, and the development of novel therapeutic agents targeting prenylation pathways.

Application

• Biochemical Research: A critical reagent for studying protein farnesylation mechanisms and enzyme kinetics.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of prenylation inhibitors for potential oncology and antiviral therapeutics.
• Proteomics & Signal Transduction Studies: Used to investigate the role of prenylated proteins in cell growth, differentiation, and oncogenic Ras protein signaling pathways.
• Peptide Synthesis: An essential building block for the solid-phase or solution-phase synthesis of farnesylated peptide analogs.
• Enzyme Substrate: Acts as a substrate for farnesyltransferase (FTase) assays in drug discovery and diagnostic development.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in related research and production.

Basic Information

Product Name	Fa-Cys(Farnesyl)-Oh
CAS No.	165245-19-2
Molecular Formula	C18H31NO3S
Molecular Weight	341.51 g/mol
Synonyms	S-Farnesyl-L-cysteine; (2R)-2-Amino-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanylpropanoic acid; L-Cysteine, S-(3,7,11-trimethyl-2,6,10-dodecatrienyl)-; Farnesylcysteine; S-trans,trans-Farnesylcysteine; N-[(E,E)-Farnesyl]-L-cysteine; Prenylated cysteine derivative
EINECS	Contact for details

Quality Control

Our Fa-Cys(Farnesyl)-Oh is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric purity. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and moisture absorption. Allow the sealed container to reach room temperature before opening to minimize condensation. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.