Description

2-Chloro-4-(Pentafluorothio)Aniline, 97% is a high-purity organofluorine building block characterized by its unique combination of an aniline core with chloro and pentafluorothio substituents. This compound matters as a versatile and critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where its specific substitution pattern enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the pentafluorothio group for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a substrate for further functionalization to create complex sulfur- and fluorine-containing molecules.
• Chemical Biology Probes: Useful in developing molecular probes and tags for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	2-Chloro-4-(Pentafluorothio)Aniline, 97%
CAS No.	165114-85-2
Molecular Formula	C6H3ClF5NS
Molecular Weight	251.61 g/mol
Synonyms	2-Chloro-4-(pentafluorosulfanyl)aniline; 4-Amino-3-chloropentafluorothioanisole; Benzenamine, 2-chloro-4-(pentafluorothio)-; 2-Chloro-4-pentafluorosulfanylaniline; 3-Chloro-4-aminopentafluorothioanisole; 2-Chloro-4-aminopentafluorothiophenol; 165114-85-2; 2-Chloro-4-(SF5)aniline
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Pentafluorothio)Aniline, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified standard. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.