Description

4-(Trimethylsilyl)Pyrimidine is a versatile organosilicon building block featuring a pyrimidine ring functionalized with a trimethylsilyl group. This compound matters for its role as a key synthetic intermediate in advanced organic and medicinal chemistry, enabling the introduction of the pyrimidine moiety under mild conditions. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in nucleoside analogs and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides that require pyrimidine-based structures.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of specialty polymers and silicon-containing advanced materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and coordination complexes.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in heterocyclic and organosilicon chemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-(Trimethylsilyl)Pyrimidine
CAS No.	164738-48-1
Molecular Formula	C7H12N2Si
Molecular Weight	152.27 g/mol
Synonyms	4-Trimethylsilylpyrimidine; Pyrimidine, 4-(trimethylsilyl)-; 4-TMS-Pyrimidine; 4-(Trimethylsilyl)pyrimidine; 4-Pyrimidinyltrimethylsilane; Trimethyl(4-pyrimidinyl)silane
EINECS	Contact for details

Quality Control

Our 4-(Trimethylsilyl)Pyrimidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.