Description

3-[[4-[2-[(3-Chlorophenyl)Amino]-4-Pyrimidinyl]-2-Pyridinyl]Amino]-1-Propanol is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitors for cancer therapy research.
• Biochemical Research: Used as a reference standard or a tool compound in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP (Good Manufacturing Practice) production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and drug discovery pathways.

Basic Information

Product Name	3-[[4-[2-[(3-Chlorophenyl)Amino]-4-Pyrimidinyl]-2-Pyridinyl]Amino]-1-Propanol
CAS No.	164658-13-3
Molecular Formula	C18H18ClN5O
Molecular Weight	355.82 g/mol
Synonyms	1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-; 3-({4-[2-(3-Chloroanilino)pyrimidin-4-yl]pyridin-2-yl}amino)propan-1-ol; N-(3-Chlorophenyl)-N'-(2-((3-hydroxypropyl)amino)pyridin-4-yl)pyrimidine-2,4-diamine; Kinase Inhibitor Intermediate; CAS 164658-13-3
EINECS	Contact for details

Quality Control

Every batch of 3-[[4-[2-[(3-Chlorophenyl)Amino]-4-Pyrimidinyl]-2-Pyridinyl]Amino]-1-Propanol is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) including HPLC purity, related substance profiles, and structural confirmation (NMR, MS) is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.