Description

H-D-Tyr-Ile-Asn-Leu-Ile-D-Thr-Arg-Gln-Arg-D-Tyr-Nh2 is a synthetic peptide sequence of significant interest in advanced biochemical research and development. This compound, with CAS number 163887-48-7, is valued for its specific structural configuration, which incorporates D-amino acids to enhance metabolic stability and biological activity. It is primarily utilized by pharmaceutical researchers and biotechnology companies engaged in peptide-based drug discovery, particularly for exploring novel therapeutic targets and developing stable peptide analogs.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active lead compound in the discovery of novel peptide therapeutics.
• Biochemical Assay Development: Used as a reference standard or target molecule in the development of high-throughput screening assays and diagnostic tests.
• Structure-Activity Relationship (SAR) Studies: Essential for investigating the impact of D-amino acid substitutions on peptide conformation, receptor binding affinity, and pharmacokinetic properties.
• Protease Stability Studies: Employed to study resistance to enzymatic degradation due to the incorporation of D-configured amino acids.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research in peptide chemistry, molecular biology, and signal transduction pathways.
• Preclinical Development: Acts as a candidate molecule for in vitro and in vivo efficacy and toxicity profiling in early-stage drug development pipelines.

Basic Information

Product Name	H-D-Tyr-Ile-Asn-Leu-Ile-D-Thr-Arg-Gln-Arg-D-Tyr-Nh2
CAS No.	163887-48-7
Molecular Formula	C58H94N18O16
Molecular Weight	1251.5 g/mol
Synonyms	H-D-Tyr-Ile-Asn-Leu-Ile-D-Thr-Arg-Gln-Arg-D-Tyr-amide; [D-Thr7, D-Tyr12]-Peptide; Argipressin antagonist fragment; D-Tyr-Ile-Asn-Leu-Ile-D-Thr-Arg-Gln-Arg-D-Tyr-NH2; Peptide V1b antagonist derivative; Cyclooxygenase-2 inhibitor peptide analog; Vasopressin receptor ligand; Custom peptide sequence 163887-48-7
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-D-Tyr-Ile-Asn-Leu-Ile-D-Thr-Arg-Gln-Arg-D-Tyr-Nh2 undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, content, and analytical results are provided with every shipment to ensure compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.