Description

Cangrelor Tetrasodium is a high-purity, direct-acting P2Y12 platelet receptor antagonist used in its tetrasodium salt form. This compound is critical for researchers and manufacturers developing antiplatelet therapies and studying cardiovascular pharmacology. It is primarily utilized by pharmaceutical R&D teams, clinical research organizations, and fine chemical suppliers serving the life sciences sector. The product is supplied as a hygroscopic, light-sensitive powder, requiring specific handling to maintain its stability and efficacy.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API): Serves as the key therapeutic agent in the formulation of antiplatelet medications.
• Biochemical Research: Used as a potent and selective tool compound to study P2Y12 receptor signaling pathways and platelet aggregation mechanisms in vitro.
• Reference Standard: Employed as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Preclinical Development: Essential for pharmacokinetic, pharmacodynamic, and toxicology studies during the drug discovery and development process.
• Formulation Studies: Used in the development of stable parenteral (intravenous) dosage forms due to its rapid-acting nature.

Basic Information

Product Name	Cangrelor Tetrasodium
CAS No.	163706-36-3
Molecular Formula	C17H22Cl2N5Na4O12P3S2
Molecular Weight	864.29 g/mol
Synonyms	Cangrelor sodium salt; AR-C69931MX tetrasodium salt; N6-(2-Methylthioethyl)-2-(3,3,3-trifluoropropylthio)-5'-adenylic acid, cyclic monohydride, tetrasodium salt; (1R,2S,3R,5R)-3-(6-Amino-2-(((methylthio)ethyl)thio)-9H-purin-9-yl)-5-((((trifluoropropyl)thio)methyl)cyclopentane-1,2-diol tetrasodium salt; AR-C 69931; AR-C69931XX; Cangrelor (tetrasodium)
EINECS	Contact for details

Quality Control

Our Cangrelor Tetrasodium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.