Description

4-Amino-3-Iodobenzotrifluoride is a high-value halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and iodine substituents make it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-generating compounds in display and lighting technologies.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct biaryl systems.
• Fluorinated Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where fluorine substitution enhances lightfastness and chemical resistance.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-Amino-3-Iodobenzotrifluoride
CAS No.	163444-17-5
Molecular Formula	C7H5F3IN
Molecular Weight	287.02 g/mol
Synonyms	3-Iodo-4-aminobenzotrifluoride; 4-Amino-α,α,α-trifluoro-3-iodotoluene; 2-Iodo-α,α,α-trifluoro-p-toluidine; 4-Amino-3-iodo-α,α,α-trifluorotoluene; 3-Iodo-4-(trifluoromethyl)aniline; 4-(Trifluoromethyl)-3-iodoaniline; 3-Iodo-α,α,α-trifluoro-p-toluidine; 4-Amino-3-iodobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Iodobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.