Description

(R)-Eperisone CAS NO 163437-00-1 is the single enantiomer form of the centrally acting muscle relaxant eperisone, offering targeted pharmacological activity. This high-purity chiral intermediate is critical for the research and development of enantiomerically pure pharmaceuticals, where stereochemistry directly impacts drug efficacy and safety. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and advanced fine chemical suppliers focused on producing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of enantiomerically pure (R)-Eperisone hydrochloride and related active pharmaceutical ingredients (APIs).
• Muscle Relaxant Research: Used in preclinical and clinical research to study the specific effects of the (R)-enantiomer on skeletal muscle tone and spasticity.
• Chiral Catalyst & Ligand Development: Serves as a precursor or model compound in the development of asymmetric synthesis methodologies and chiral auxiliaries.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and chiral separation methods for quality control and pharmacokinetic studies.
• Metabolite Studies: Used in the synthesis and identification of specific drug metabolites for toxicological and ADME (Absorption, Distribution, Metabolism, and Excretion) profiling.

Basic Information

Product Name	(R)-Eperisone
CAS No.	163437-00-1
Molecular Formula	C17H25NO
Molecular Weight	259.39 g/mol
Synonyms	(R)-1-(4-Ethylphenyl)-2-methyl-3-(1-piperidinyl)-1-propanone; (R)-4'-Ethyl-2-methyl-3-(1-piperidinyl)propiophenone; (R)-Eperisone Base; (-)-Eperisone; (R)-Mional; (R)-Myonal; UNII-1K860D0S8K
EINECS	Contact for details

Quality Control

Our (R)-Eperisone is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.