Description

5-Aminolevulinic Acid Benzyl Ester Hydrochloride is a chemically protected derivative of 5-aminolevulinic acid (5-ALA), a key biochemical precursor in the heme biosynthesis pathway. This compound is of significant commercial and research interest due to its enhanced stability and cell permeability compared to the parent 5-ALA, making it a crucial intermediate in photodynamic therapy (PDT) research and pharmaceutical development. It is primarily sought by manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for developing novel diagnostic and therapeutic agents.

Application

• Photodynamic Therapy (PDT) Research: As a prodrug for the endogenous synthesis of Protoporphyrin IX (PpIX), a photosensitizer used in cancer treatment and antimicrobial applications.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex porphyrin-based drugs and diagnostic compounds.
• Biochemical Research: Used in studies of the heme biosynthesis pathway, cellular metabolism, and mechanisms of photosensitization.
• Cosmeceutical Development: Investigated for potential use in topical formulations targeting skin conditions, leveraging its role in cellular processes.
• Agrochemical Research: Explored for developing novel compounds that interfere with porphyrin biosynthesis in pests and pathogens.

Basic Information

Product Name	5-Aminolevulinic Acid Benzyl Ester Hydrochloride
CAS No.	163271-32-7
Molecular Formula	C13H18N2O3 • HCl
Molecular Weight	286.75 g/mol (Free base: 250.29 g/mol)
Synonyms	5-ALA Benzyl Ester Hydrochloride; 5-Aminolevulinic Acid Benzyl Ester HCl; Benzyl 5-Amino-4-oxopentanoate Hydrochloride; δ-Aminolevulinic Acid Benzyl Ester Hydrochloride; 5-ALA-OBzl • HCl; ALA Benzyl Ester Hydrochloride; 4-Oxo-5-aminopentanoic Acid Benzyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Aminolevulinic Acid Benzyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.