Description

Orbofiban CAS NO 163250-90-6 is a potent and selective non-peptide glycoprotein IIb/IIIa (GP IIb/IIIa) receptor antagonist. This compound is of significant interest in pharmaceutical research and development for its antiplatelet and antithrombotic properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in cardiovascular drug discovery and the development of novel therapeutic agents for thrombosis prevention.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of antiplatelet medications.
• Biochemical Research: Used as a selective tool compound to study platelet aggregation mechanisms and GP IIb/IIIa receptor function in vitro.
• Cardiovascular Disease Models: Employed in preclinical studies to investigate efficacy in models of arterial thrombosis, myocardial infarction, and stroke.
• Analytical Method Development: Acts as a critical standard for developing and validating HPLC, LC-MS, and other analytical methods for purity and potency assessment.
• Formulation Studies: Utilized in the development of various drug delivery systems, including oral formulations, to enhance bioavailability and stability.

Basic Information

Item	Detail
Product Name	Orbofiban
CAS No.	163250-90-6
Molecular Formula	C25H31FN2O5
Molecular Weight	458.53 g/mol
Synonyms	Orbofiban; L-734,217; (2S)-2-[(4-{4-[(Aminosulfonyl)amino]phenyl}-1-piperidinyl)carbonyl]amino]-3-(4-fluorophenyl)propanoic acid; SC-57099B; SC 57099B; SC-57099; GP IIb/IIIa antagonist L-734,217
EINECS	Contact for details

Quality Control

Our Orbofiban is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and LC-MS. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.