Description

2-Pyrimidinamine, 5-Fluoro-n-Methyl- (9Ci) is a fluorinated pyrimidine derivative, a high-value building block in advanced organic synthesis. This compound is crucial for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular design. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in oncology and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require fluorinated heterocyclic cores for improved efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalysis or as a component in metal-organic frameworks (MOFs).
• Material Science Precursor: Can be utilized in the synthesis of advanced organic electronic materials or liquid crystals.

Basic Information

Product Name	2-Pyrimidinamine, 5-Fluoro-n-Methyl- (9Ci)
CAS No.	163082-52-8
Molecular Formula	C5H6FN3
Molecular Weight	127.12 g/mol
Synonyms	5-Fluoro-N-methylpyrimidin-2-amine; 5-Fluoro-2-(methylamino)pyrimidine; N-Methyl-5-fluoropyrimidin-2-amine; 2-Amino-5-fluoro-N-methylpyrimidine; 5-Fluoro-2-methylaminopyrimidine; 163082-52-8; 5-Fluoro-N-methyl-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinamine, 5-Fluoro-n-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.