Description

C-Telopeptide is a specific biochemical marker peptide derived from the C-terminal end of type I collagen, a key structural protein in bone. This compound is of significant value in biomedical research and diagnostics for its role in assessing bone metabolism and resorption rates. It is primarily utilized by pharmaceutical researchers, clinical diagnostic developers, and academic institutions focused on osteoporosis, arthritis, and other metabolic bone diseases.

Application

• Biomarker Research: Critical for studying bone turnover, osteoporosis progression, and the efficacy of anti-resorptive therapies.
• Diagnostic Assay Development: Serves as a reference standard or antigen in the development and calibration of immunoassays (e.g., ELISA) for measuring CTX (C-terminal telopeptide) levels in serum or urine.
• Pharmaceutical R&D: Used in drug discovery and preclinical studies targeting bone diseases to evaluate compound effects on collagen degradation.
• Clinical Studies: Employed as a calibrator or control in clinical trials monitoring bone metastasis or the skeletal health impacts of various treatments.
• Biochemical Reagent: Functions as a high-purity substrate or inhibitor in enzymatic studies related to collagenase and cathepsin K activity.

Basic Information

Item	Detail
Product Name	C-Telopeptide
CAS No.	162929-64-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CTX; Carboxy-terminal telopeptide of type I collagen; Collagen type I C-telopeptide; α-1 type I collagen C-telopeptide; Bone collagen degradation marker; ICTP (related fragment); EKAHDGGR (common sequence); Cross-linked C-telopeptide
EINECS	Contact for details

Quality Control

Our C-Telopeptide is produced and tested under strict quality management systems suitable for research and diagnostic applications. Each batch undergoes rigorous analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.