Description

Proline, 3-Hydroxy-5-Imino-1-Methyl- (9Ci) is a specialized, non-proteinogenic proline derivative characterized by its unique imino and hydroxy functional groups. This compound serves as a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex heterocyclic compounds and potential drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in protease inhibitor and neurological drug discovery.
• Agrochemical Synthesis: Used as a precursor in the manufacture of specialized herbicides and plant growth regulators that target specific enzymatic pathways.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate proline metabolism and related biological processes.
• Peptidomimetics: Integral for designing and synthesizing peptide analogs with enhanced stability and bioavailability for therapeutic applications.
• Asymmetric Catalysis: Serves as a chiral auxiliary or ligand precursor in asymmetric synthesis to induce stereoselectivity in chemical reactions.
• Fine Chemical Production: A building block for the synthesis of complex, high-value specialty chemicals used in various advanced material applications.

Basic Information

Item	Detail
Product Name	Proline, 3-Hydroxy-5-Imino-1-Methyl- (9Ci)
CAS No.	162763-50-0
Molecular Formula	C6H10N2O2
Molecular Weight	142.16 g/mol
Synonyms	1-Methyl-3-hydroxy-5-iminopyrrolidine-2-carboxylic acid; 3-Hydroxy-5-imino-1-methylproline; 5-Imino-1-methyl-3-hydroxyproline; (2S)-1-Methyl-3-hydroxy-5-iminopyrrolidine-2-carboxylic acid; 1-Methyl-3-hydroxy-5-iminoproline; L-Proline, 3-hydroxy-5-imino-1-methyl-; 5-Imino-3-hydroxy-1-methyl-L-proline; 3-Hydroxy-1-methyl-5-iminoproline
EINECS	Contact for details

Quality Control

We maintain a strict quality management system aligned with cGMP principles for fine chemicals. Every batch of Proline, 3-Hydroxy-5-Imino-1-Methyl- (9Ci) is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.