Description

4-Bromo-2,6-Difluorobenzyl Bromide is a versatile and highly reactive benzyl bromide derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its value lies in the strategic positioning of both bromine and fluorine substituents, which enable precise molecular construction and the introduction of key pharmacophores. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require a reliable, high-purity intermediate for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluorobenzyl moiety enhances biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the creation of monomers and functionalized polymers, including liquid crystals and organic electronic materials.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry, facilitating structure-activity relationship (SAR) studies and route scouting.
• Fluorine Chemistry: Acts as a pivotal intermediate for further functionalization, introducing fluorine atoms into complex molecular architectures.

Basic Information

Product Name	4-Bromo-2,6-Difluorobenzyl Bromide
CAS No.	162744-60-7
Molecular Formula	C7H4Br2F2
Molecular Weight	289.91 g/mol
Synonyms	1-(Bromomethyl)-4-bromo-2,6-difluorobenzene; (4-Bromo-2,6-difluorophenyl)methyl bromide; 2,6-Difluoro-4-bromobenzyl bromide; α,4-Dibromo-2,6-difluorotoluene; 4-Bromo-α-bromo-2,6-difluorotoluene; Benzene, 1-(bromomethyl)-4-bromo-2,6-difluoro-; 4-Bromo-2,6-difluorobenzylbromide
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-Difluorobenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and industrial intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.