Description

4-Bromo-2,6-Difluorobenzyl Alcohol is a versatile halogenated benzyl alcohol derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of bromine and fluorine substituents, which enable selective functionalization and are key to modulating the electronic and steric properties of target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the difluoro and bromo groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen functionalities.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	4-Bromo-2,6-Difluorobenzyl Alcohol
CAS No.	162744-59-4
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	(4-Bromo-2,6-difluorophenyl)methanol; 2,6-Difluoro-4-bromobenzyl alcohol; 4-Bromo-2,6-difluorobenzenemethanol; α-Hydroxymethyl-4-bromo-2,6-difluorobenzene; 4-Bromo-α,α-difluorobenzyl alcohol; Benzenemethanol, 4-bromo-2,6-difluoro-; 162744-59-4; 4-Br-2,6-F2-BnOH
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-Difluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.