Description

4-Bromo-2,3-Difluorobenzylalcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on a benzyl alcohol core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluorobenzyl moiety enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronics: Building block for creating charge-transport materials and emissive layers in OLEDs and other electronic devices.
• Cross-Coupling Reactions: The bromine atom acts as a handle for palladium-catalyzed reactions (e.g., Suzuki, Heck), enabling rapid diversification of the molecular scaffold.
• Material Science Research: Utilized in developing novel polymers and functional materials with specific optical or electronic characteristics.

Basic Information

Product Name	4-Bromo-2,3-Difluorobenzylalcohol
CAS No.	162744-55-0
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	(4-Bromo-2,3-difluorophenyl)methanol; 2,3-Difluoro-4-bromobenzyl alcohol; 4-Bromo-2,3-difluorobenzenemethanol; α-Hydroxymethyl-4-bromo-2,3-difluorobenzene; Benzenemethanol, 4-bromo-2,3-difluoro-; 4-Bromo-2,3-difluoro benzylalcohol; 162744-55-0; Benzyl alcohol, 4-bromo-2,3-difluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,3-Difluorobenzylalcohol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and aligns with ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.