Description

H-Leu-Ser-Lys-Leu-Oh is a synthetic tetrapeptide sequence composed of leucine, serine, lysine, and leucine residues. This compound is of significant interest in biochemical and pharmaceutical research for its potential role in studying protein-protein interactions, enzyme substrates, and as a building block for more complex peptide structures. It serves as a critical intermediate for researchers and manufacturers in the life sciences sector, particularly in drug discovery and development. The product is supplied as a high-purity material suitable for advanced research applications.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and screening of novel therapeutic peptides.
• Biochemical Studies: Serves as a substrate or inhibitor model for investigating protease and kinase activity in enzymatic assays.
• Peptide Library Construction: Acts as a fundamental building block in the combinatorial synthesis of peptide libraries for high-throughput screening.
• Cell Biology Research: Employed in studies of cell signaling pathways, receptor-ligand interactions, and intracellular transport mechanisms.
• Cosmeceutical Development: Investigated for potential bioactive properties in advanced skincare and cosmetic formulations.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, peptide science, and medicinal chemistry.

Basic Information

Product Name	H-Leu-Ser-Lys-Leu-Oh
CAS No.	162559-45-7
Molecular Formula	C23H44N6O7
Molecular Weight	516.63 g/mol
Synonyms	L-Leucyl-L-seryl-L-lysyl-L-leucine; Leu-Ser-Lys-Leu; H-Leu-Ser-Lys-Leu-OH tetrapeptide; LSKL peptide; Tetrapeptide Leu-Ser-Lys-Leu; (2S)-2-[[(2S)-2-[[(2S)-2,6-Diaminohexanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]-L-leucine; L-Leu-L-Ser-L-Lys-L-Leu
EINECS	Contact for details

Quality Control

Our H-Leu-Ser-Lys-Leu-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment. We support compliance with cGMP guidelines for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For prolonged storage under inert atmosphere, contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Amino Acid Ratio	Within theoretical ± 10%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.