Description

Melanocyte Protein Pmel 17 (130-138) (Human) is a synthetic peptide fragment corresponding to residues 130-138 of the human Pmel17 glycoprotein, a key component in melanosome biogenesis. This high-purity peptide is critical for fundamental research into melanin synthesis pathways, pigment cell biology, and related disorders. It serves as an essential biochemical tool for scientists and developers in academic research, pharmaceutical R&D, and diagnostic assay development, particularly for studies involving melanoma and pigmentation.

Application

• Biochemical Research: Used as a reference standard or antigen in studies of melanosome structure, function, and melanogenesis regulation.
• Immunological Studies: Employed in the development and validation of antibodies specific to the Pmel17 protein epitope.
• Cell Biology: Applied in cellular assays to investigate protein-protein interactions, trafficking, and processing within melanocytes.
• Disease Mechanism Investigation: A vital reagent for exploring the molecular basis of pigmentary disorders and melanoma progression.
• Diagnostic Development: Potential use as a component in ELISA or other immunoassays for detecting Pmel17-related biomarkers.
• Peptide Mapping: Serves as a confirmed sequence fragment for mass spectrometry analysis and protein characterization.

Basic Information

Product Name	Melanocyte Protein Pmel 17 (130-138) (Human)
CAS No.	162558-08-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PMEL17 (130-138); gp100 (130-138); SILV (130-138); Melanocyte lineage-specific antigen gp100; Pmel 17 peptide fragment; Human Pmel17 residues 130-138; ME20 antigen; Preferentially expressed antigen in melanoma (130-138)
EINECS	Contact for details

Quality Control

Our Melanocyte Protein Pmel 17 (130-138) (Human) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological reliability. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for sequence confirmation. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Solubility	Soluble in water or dilute acetic acid
Amino Acid Analysis	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.