Description

n-Methylphenylalanyl-Prolyl-Arginine is a synthetic tripeptide derivative of significant interest in advanced biochemical research and development. This compound is valued for its role as a specialized building block and a model substrate in the study of enzymatic processes and peptide-based interactions. It is primarily utilized by research institutions and pharmaceutical developers focused on protease mechanisms, peptide mimetics, and novel therapeutic agent discovery. The material is supplied to exacting standards to ensure consistency and reliability for critical laboratory and pre-clinical applications.

Application

• Biochemical Research: Serves as a key substrate or inhibitor in studies of serine proteases, particularly thrombin and related enzymes.
• Pharmaceutical Development: Used as an intermediate or a reference standard in the discovery and optimization of peptide-based drug candidates targeting coagulation pathways.
• Enzymology Studies: Employed to investigate enzyme kinetics, specificity, and inhibition mechanisms due to its arginine-proline sequence motif.
• Diagnostic Reagent Formulation: Acts as a component in the development of specialized in-vitro diagnostic assays for hemostasis and thrombosis.
• Academic Research: Provides a tool for universities and research institutes exploring protein-peptide interactions and signal transduction pathways.
• Peptide Library Synthesis: Used as a building block in the combinatorial synthesis of focused peptide libraries for high-throughput screening.

Basic Information

Product Name	n-Methylphenylalanyl-Prolyl-Arginine
CAS No.	162435-91-8
Molecular Formula	C22H33N7O4
Molecular Weight	459.55 g/mol
Synonyms	N-Methyl-Phe-Pro-Arg; MePhe-Pro-Arg; Methylphenylalanyl-prolyl-arginine; L-Phenylalanine, N-methyl-, 1-(N-L-arginyl-L-prolyl)-; Thrombin Inhibitor Peptide Fragment; H-MePhe-Pro-Arg-OH; Argatroban Related Compound; Benzyloxycarbonyl-MePhe-Pro-Arg precursor
EINECS	Contact for details

Quality Control

Every batch of n-Methylphenylalanyl-Prolyl-Arginine is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Total Peptide Content)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.