Description

6-(Trifluoromethoxy)-1H-Indole-2,3-Dione is a high-value, fluorinated isatin derivative, a key heterocyclic building block in advanced organic synthesis. Its unique trifluoromethoxy-substituted indole-2,3-dione scaffold makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability. This compound is primarily sought by research and development chemists in the pharmaceutical industry for the synthesis of potential drug candidates, as well as by agrochemical researchers for creating new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex molecules for drug discovery programs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for improved lipophilicity and biological activity.
• Material Science: Used in the research and development of specialty chemicals and advanced organic materials, including dyes and functional polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new synthetic pathways involving fluorinated heterocycles.

Basic Information

Product Name	6-(Trifluoromethoxy)-1H-Indole-2,3-Dione
CAS No.	162252-92-8
Molecular Formula	C9H4F3NO3
Molecular Weight	231.13 g/mol
Synonyms	6-(Trifluoromethoxy)isatin; 6-(Trifluoromethoxy)-2,3-dihydro-1H-indole-2,3-dione; 6-(Trifluoromethoxy)-1H-indole-2,3-dione; 6-Trifluoromethoxyisatin; 1H-Indole-2,3-dione, 6-(trifluoromethoxy)-; Isatin, 6-(trifluoromethoxy)-; 6-(Trifluoromethoxy)indoline-2,3-dione
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethoxy)-1H-Indole-2,3-Dione is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global B2B clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.