Description

4,7-Dichloro-6-Nitroquinazoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel quinazoline-based compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other targeted cancer therapeutics.
• Agrochemical Research: Used in the development of novel herbicides and fungicides based on the quinazoline scaffold.
• Chemical Synthesis Building Block: Serves as a versatile substrate for nucleophilic substitution reactions, enabling the introduction of various amines and other functional groups at the 4 and 7 positions.
• Material Science: Investigated as a monomer or precursor for the creation of organic electronic materials and photoactive compounds.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4,7-Dichloro-6-Nitroquinazoline
CAS No.	162012-71-7
Molecular Formula	C8H3Cl2N3O2
Molecular Weight	244.04 g/mol
Synonyms	6-Nitro-4,7-dichloroquinazoline; 4,7-Dichloro-6-nitro-quinazoline; Quinazoline, 4,7-dichloro-6-nitro-; 162012-71-7; 4,7-Dichloro-6-nitro-quinazoline; 4,7-Dichloro-6-nitroquinazoline; 6-Nitro-4,7-dichloro-quinazoline
EINECS	Contact for details

Quality Control

Our 4,7-Dichloro-6-Nitroquinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.