Description

Grepafloxacin Hydrochloride is a synthetic fluoroquinolone antibiotic compound, recognized for its potent broad-spectrum antibacterial activity. Its primary commercial value lies in its role as a key pharmaceutical intermediate for the research and development of advanced antimicrobial agents. This product is essential for pharmaceutical manufacturers, research institutions, and chemical suppliers serving the global life sciences sector. Grepafloxacin Hydrochloride CAS NO 161967-81-3 is critical for applications demanding high-purity active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of finished antibiotic dosage forms.
• Active Pharmaceutical Ingredient (API): Serves as the core therapeutic agent in antimicrobial formulations targeting respiratory and urinary tract infections.
• Research & Development: Used in preclinical and clinical studies to investigate new antibacterial therapies and mechanisms of action.
• Reference Standard: Employed in analytical laboratories for quality control, method validation, and regulatory compliance testing.
• Chemical Synthesis: A versatile intermediate for medicinal chemists exploring novel fluoroquinolone derivatives with enhanced properties.

Basic Information

Product Name	Grepafloxacin Hydrochloride
CAS No.	161967-81-3
Molecular Formula	C19H22FN3O3•HCl
Molecular Weight	395.86 g/mol (Free base: 359.40)
Synonyms	Grepafloxacin HCl; (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid hydrochloride; OPC-17116; (RS)-Grepafloxacin hydrochloride; 7-(3-Methylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Grepafloxacin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) are provided with every shipment, detailing all test results against relevant pharmacopeial standards (such as USP/EP) where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.