Description

Glp-1 (9-36) Amide (Human, Bovine, Guinea Pig, Mouse, Porcine, Rat) is a bioactive peptide fragment derived from the glucagon-like peptide-1 (GLP-1) hormone, a key regulator of insulin secretion and glucose metabolism. This specific amide form is critical for advanced pharmacological research and drug discovery programs targeting metabolic disorders such as type 2 diabetes and obesity. It serves as an essential reference standard and active pharmaceutical ingredient (API) intermediate for scientists and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Reference Standard for Bioanalytical Assays: Used in HPLC, LC-MS, and ELISA methods to quantify GLP-1 levels in preclinical and clinical studies.
• Pharmacological Research: Investigating the metabolic effects, receptor binding affinity, and degradation pathways of GLP-1 hormone fragments.
• Drug Discovery & Development: Serving as a key intermediate or lead compound in the development of novel GLP-1 receptor agonists and related therapeutics.
• Biochemical Tool: Utilized in cell-based assays and signal transduction studies to understand insulin secretion mechanisms.
• Quality Control (QC) Testing: Acting as a system suitability standard in the purity and potency analysis of GLP-1-based pharmaceutical products.

Basic Information

Item	Detail
Product Name	Glp-1 (9-36) Amide (Human, Bovine, Guinea Pig, Mouse, Porcine, Rat)
CAS No.	161748-29-4
Molecular Formula	C149H226N40O45
Molecular Weight	3299.7 g/mol
Synonyms	GLP-1 (9-36) amide; Glucagon-like peptide 1 (9-36) amide; GLP-1 amide fragment 9-36; GLP-1 (7-36) amide metabolite; Incretin hormone fragment; Tirzepatide metabolite reference standard; GLP-1 receptor ligand; H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
EINECS	Contact for details

Quality Control

Our Glp-1 (9-36) Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.