Description

Aminobenzoyl-Arg-Val-Lys-Arg-Gly-Leu-Ala-Tyr(No2)-Asp CAS NO 161721-77-3 is a synthetic, nitrotyrosine-containing peptide sequence designed for advanced biochemical research and development. This compound serves as a critical tool for studying protease activity, signal transduction pathways, and the role of specific amino acid motifs in protein function. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on enzymology, drug discovery, and proteomics.

Application

• Protease Substrate & Inhibitor Screening: Used as a specific chromogenic or fluorogenic substrate to assay the activity of target proteases, including furin and related proprotein convertases.
• Biochemical Research: Serves as a model peptide for investigating enzyme kinetics, cleavage specificity, and inhibition mechanisms in vitro.
• Pharmaceutical Development: Employed in the discovery and optimization of therapeutic agents targeting specific proteolytic enzymes involved in disease pathways.
• Diagnostic Reagent Component: Can be integrated into diagnostic kits and assays designed to detect or quantify specific protease activity in biological samples.
• Cell Biology Studies: Utilized to study intracellular processing events and the role of specific peptide sequences in cellular signaling and protein maturation.

Basic Information

Product Name	Aminobenzoyl-Arg-Val-Lys-Arg-Gly-Leu-Ala-Tyr(No2)-Asp
CAS No.	161721-77-3
Molecular Formula	C58H90N20O17
Molecular Weight	1307.5 g/mol
Synonyms	Abz-RVKRGLAY(NO2)D; 4-Aminobenzoyl-Arg-Val-Lys-Arg-Gly-Leu-Ala-Tyr(3-NO2)-Asp; Furin Substrate Peptide; p-Aminobenzoyl-RVKRGLAY(NO2)D; Fluorogenic Furin Substrate; Chromogenic Peptide Substrate; Proprotein Convertase Substrate; PC Substrate
EINECS	Contact for details

Quality Control

Our Aminobenzoyl-Arg-Val-Lys-Arg-Gly-Leu-Ala-Tyr(No2)-Asp is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.