Description

(Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) is a synthetic peptide fragment derived from the endogenous neurotransmitter Neuropeptide Y (NPY). This specific analog, with modifications at positions 30, 32, and 34, is primarily utilized in advanced biochemical and pharmacological research to study NPY receptor interactions and signaling pathways. It serves as a critical tool for researchers in neuroscience, endocrinology, and drug discovery who require high-purity, well-characterized peptide ligands for receptor binding assays and functional studies.

Application

• Neuroscience Research: Investigation of NPY receptor subtypes (Y1, Y2, Y4, Y5, Y6) and their role in appetite regulation, anxiety, and cardiovascular function.
• Pharmacological Studies: Used as a reference standard or competitive ligand in receptor binding assays and functional cellular assays to evaluate novel drug candidates.
• Biochemical Tool: Study of peptide-receptor interaction mechanisms, structure-activity relationships (SAR), and signal transduction pathways.
• Endocrine Research: Exploration of NPY's effects on energy homeostasis, stress response, and hormonal regulation.
• Academic & Institutional R&D: Fundamental research in universities and research institutes focusing on neuropeptide biology and peptide chemistry.
• Pharmaceutical Development: Early-stage discovery research for metabolic disorders, neurological conditions, and cardiovascular diseases.

Basic Information

Product Name	(Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36)
CAS No.	161650-01-7
Molecular Formula	C55H81N13O12
Molecular Weight	1116.3 g/mol
Synonyms	NPY (28-36), [Pro30, Tyr32, Leu34] NPY (28-36); Neuropeptide Y (28-36) fragment; NPY fragment (28-36); [Pro30, Tyr32, Leu34]-NPY (28-36); Tyr-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2 (modified); NPY analog (28-36); NPY receptor ligand fragment
EINECS	Contact for details

Quality Control

Our (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency, critical for reliable research outcomes. Each batch undergoes comprehensive analytical characterization, including reverse-phase HPLC for purity assessment and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Conforms to theoretical composition
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.