Description

4-(2-Methoxyethylamino)-3-Nitrobenzotrifluoride is a specialized aromatic trifluoromethyl compound featuring both nitro and methoxyethylamino functional groups. This unique structure makes it a valuable and versatile advanced pharmaceutical intermediate and organic synthesis building block. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethylphenyl moiety for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the nitro and amino groups serve as handles for further chemical modification.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating specialized fluorinated aromatic compounds used in electronic display technologies.
• Dye & Pigment Intermediate: Employed in the synthesis of complex, color-fast dyes and organic pigments due to its electron-withdrawing substituents.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating biaryl structures.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-(2-Methoxyethylamino)-3-Nitrobenzotrifluoride
CAS No.	161605-63-6
Molecular Formula	C10H11F3N2O3
Molecular Weight	264.20 g/mol
Synonyms	3-Nitro-4-[(2-methoxyethyl)amino]benzotrifluoride; 1-Methoxy-2-[(4-trifluoromethyl-2-nitrophenyl)amino]ethane; 4-(2-Methoxyethylamino)-3-nitro-α,α,α-trifluorotoluene; 2-Methoxy-N-(4-trifluoromethyl-2-nitrophenyl)ethanamine; 4-(2-Methoxyethylamino)-3-nitrobenzotrifluoride; Benzenamine, 4-(trifluoromethyl)-2-nitro-N-(2-methoxyethyl)-; N-(2-Methoxyethyl)-4-(trifluoromethyl)-2-nitroaniline
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Methoxyethylamino)-3-Nitrobenzotrifluoride is produced under a strict quality management system and undergoes comprehensive analytical testing. We ensure high purity and batch-to-batch consistency to meet the stringent requirements of advanced synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. Our quality protocols are designed to support cGMP-compliant applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.