Description

Trihexyphenidyl n-Oxide is a high-purity chemical compound of significant interest in advanced pharmaceutical research and development. Its primary value lies as a key intermediate or reference standard in the synthesis and analytical profiling of active pharmaceutical ingredients (APIs), particularly within the central nervous system (CNS) therapeutic area. This product is essential for research laboratories, analytical service providers, and pharmaceutical manufacturers engaged in method development, quality control, and novel drug discovery processes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of specialized active pharmaceutical ingredients (APIs) and related compounds.
• Analytical Reference Standard: Used for method development, validation, and quality control (QC) testing in HPLC, GC, and LC-MS analyses to ensure accuracy and compliance.
• Metabolite Studies: Employed in pharmacological and toxicological research to study drug metabolism pathways and identify oxidative metabolites.
• Impurity Profiling: Acts as a certified reference material for the identification and quantification of process-related impurities and degradation products in drug substances.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) settings for fundamental neurochemical research and preclinical studies.
• Regulatory Documentation: Provides essential material for compiling regulatory submission dossiers (e.g., for FDA, EMA) requiring full characterization of drug substances and their related substances.

Basic Information

Product Name	Trihexyphenidyl n-Oxide
CAS No.	161564-79-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Trihexyphenidyl N-Oxide; 1-Cyclohexyl-1-phenyl-3-(1-piperidinyl)-1-propanol N-Oxide; Benzhexol N-Oxide; Artane N-Oxide; Trihexyphenidyl Oxide; Trihex N-Oxide; 1-Piperidinepropanol, α-cyclohexyl-α-phenyl-, N-oxide
EINECS	Contact for details

Quality Control

Every batch of Trihexyphenidyl n-Oxide is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.