Description

(D-Arg32)-Antistasin (32-38) CAS NO 161561-46-2 is a synthetic peptide fragment derived from the natural anticoagulant protein antistasin. This compound is a critical research tool for investigating the mechanisms of blood coagulation and the inhibition of specific serine proteases, particularly factor Xa. It is primarily utilized by researchers and developers in the fields of pharmaceutical R&D, biochemistry, and hematology for studying thrombosis and developing novel therapeutic agents.

Application

• Biochemical Research: Used as a specific inhibitor in enzymatic assays to study the activity and regulation of coagulation factor Xa.
• Pharmaceutical Development: Serves as a reference standard and lead compound in the discovery and optimization of new anticoagulant and antithrombotic drugs.
• Mechanistic Studies: Employed to elucidate the structure-activity relationships (SAR) of antistasin-derived peptides and their interaction with target proteases.
• In Vitro Diagnostics: Can be used as a component in specialized diagnostic kits for monitoring coagulation pathways.
• Academic Research: A key reagent for university and institutional labs focusing on cardiovascular biology, hemostasis, and protease biology.

Basic Information

Product Name	(D-Arg32)-Antistasin (32-38)
CAS No.	161561-46-2
Molecular Formula	C37H64N14O11S
Molecular Weight	889.06 g/mol
Synonyms	Antistasin (32-38), D-Arg32; Antistasin Fragment 32-38; [D-Arg32]-Antistasin (32-38); H-Ile-Gly-Gly-Arg-Leu-Arg-Gln-OH (D-Arg32 variant); Factor Xa Inhibitor Peptide (32-38); IGG(D-R)LRQ; Coagulation Factor Xa Inhibitor Peptide Fragment
EINECS	Contact for details

Quality Control

Every batch of (D-Arg32)-Antistasin (32-38) is produced and analyzed under stringent quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure high purity and batch-to-batch consistency essential for research. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.