Description

4-Iodo-6-Methoxypyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its core value lies in providing a reactive iodine site for cross-coupling reactions, enabling the efficient construction of complex heterocyclic systems. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating functionalized polymers and liquid crystals.
• Cross-Coupling Reactions: Essential substrate for Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
• Chemical Biology: Used in the synthesis of probes and labeled compounds for biochemical studies.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Iodo-6-Methoxypyrimidine
CAS No.	161489-05-0
Molecular Formula	C5H5IN2O
Molecular Weight	236.01 g/mol
Synonyms	6-Methoxy-4-iodopyrimidine; 4-Iodo-6-methoxypyrimidine; 6-Methoxy-4-iodo-pyrimidine; Pyrimidine, 4-iodo-6-methoxy-; 4-Iodo-6-methoxy-pyrimidine; 161489-05-0; 4-Iodo-6-methoxypyrimidine (CAS 161489-05-0)
EINECS	Contact for details

Quality Control

Our 4-Iodo-6-Methoxypyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.