Description

Pyrimidine, 2-Ethynyl-4-Methoxy- (9Ci) is a specialized heterocyclic building block featuring a reactive ethynyl group and a methoxy substituent on the pyrimidine core. This compound is valued for its role as a key synthetic intermediate in the development of advanced pharmaceutical compounds and agrochemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor for advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways due to its click-chemistry compatible alkyne group.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic systems via Sonogashira and other cross-coupling reactions.

Basic Information

Product Name	Pyrimidine, 2-Ethynyl-4-Methoxy- (9Ci)
CAS No.	161489-04-9
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	2-Ethynyl-4-methoxypyrimidine; 4-Methoxy-2-ethynylpyrimidine; 2-Ethynyl-4-methoxy-pyrimidine; 2-Ethynyl-4-methoxypyrimidine (9CI); 161489-04-9; 4-Methoxy-2-ethynyl-pyrimidine; Pyrimidine, 2-ethynyl-4-methoxy-
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 2-Ethynyl-4-Methoxy- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized and should be handled under an inert atmosphere when opened.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.