Description

3-Chloro-4-Fluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its dual functional groups, which allow for selective chemical transformations, making it a critical intermediate in the development of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the chloro-fluoro substitution pattern confers specific biological activity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer Chemistry: Employed as a monomer or modifier to introduce aromatic and fluorinated units into specialty polymers, enhancing their chemical resistance and thermal stability.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions, esterifications, and etherifications as a benzyl alcohol derivative.
• Chemical Research & Development: A valuable standard and starting material in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	3-Chloro-4-Fluorobenzyl Alcohol
CAS No.	161446-90-8
Molecular Formula	C7H6ClFO
Molecular Weight	160.57 g/mol
Synonyms	(3-Chloro-4-fluorophenyl)methanol; 3-Chloro-4-fluorobenzenemethanol; 1-Chloro-2-fluoro-4-(hydroxymethyl)benzene; 4-Fluoro-3-chlorobenzyl Alcohol; 3-Chloro-4-fluoro benzyl alcohol; 3-Chloro-4-fluoro-benzenemethanol; 3-Chloro-4-fluoro-benzylalcohol; 3-Chloro-4-fluorobenzylalcohol
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Fluorobenzyl Alcohol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We operate under a quality system aligned with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.