Description

2,6-Dibromoquinazoline is a high-purity halogenated quinazoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual bromine substitution pattern, which provides versatile reactivity for cross-coupling reactions and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or functional unit in the development of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create complex biaryl and heteroaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2,6-Dibromoquinazoline
CAS No.	161425-75-8
Molecular Formula	C8H4Br2N2
Molecular Weight	287.94 g/mol
Synonyms	Quinazoline, 2,6-dibromo-; 2,6-Dibromo-quinazoline; 2,6-Dibromoquinazoline; 161425-75-8; Dibromoquinazoline; NSC 405124; AKOS005258155; AS-80533; ZINC000003869756; BRN 0877415
EINECS	Contact for details

Quality Control

Our 2,6-Dibromoquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.