Description

Ethyl 4-(4-Methoxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, offering a reliable building block for research and production. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex heterocyclic APIs, particularly in central nervous system (CNS) and cardiovascular drug research.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct novel pyrimidine and dihydropyrimidinone derivatives with potential biological activity.
• Medicinal Chemistry Research: Enables the exploration of structure-activity relationships (SAR) for new drug candidates in academic and industrial R&D settings.
• Contract Manufacturing: Supplied to CMOs and CDMOs for the scale-up and commercial production of proprietary pharmaceutical compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a high degree of structural specificity and purity.

Basic Information

Product Name	Ethyl 4-(4-Methoxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate
CAS No.	161374-07-8
Molecular Formula	C15H18N2O4
Molecular Weight	290.31 g/mol
Synonyms	Ethyl 4-(4-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(4-methoxyphenyl)-6-methyl-2-oxo-, ethyl ester; 4-(4-Methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylic acid ethyl ester; DHPM derivative; Biginelli reaction product; Dihydropyrimidinone derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ethyl 4-(4-Methoxyphenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydro-5-Pyrimidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.