Description

n-(Chloroacetyl)-4-(Trifluoromethoxy)Aniline is a high-purity, specialized organic intermediate featuring both a chloroacetyl and a trifluoromethoxy functional group. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethoxy group.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials with specific thermal or chemical resistance properties.
• Chemical Biology & Proteomics: Employed as a reagent for modifying peptides or proteins, or in the synthesis of molecular probes for biological studies.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring the introduction of a chloroacetyl moiety onto an aniline derivative.

Basic Information

Product Name	n-(Chloroacetyl)-4-(Trifluoromethoxy)Aniline
CAS No.	161290-85-3
Molecular Formula	C9H7ClF3NO2
Molecular Weight	253.61 g/mol
Synonyms	N-(Chloroacetyl)-4-(trifluoromethoxy)aniline; 2-Chloro-N-[4-(trifluoromethoxy)phenyl]acetamide; 4'-(Trifluoromethoxy)chloroacetanilide; 2-Chloro-N-[4-(trifluoromethoxyphenyl)]acetamide; 2-Chloroacetamide, N-[4-(trifluoromethoxy)phenyl]-; 4-Trifluoromethoxychloroacetanilide; 4-(Trifluoromethoxy)phenylchloroacetamide
EINECS	Contact for details

Quality Control

Our n-(Chloroacetyl)-4-(Trifluoromethoxy)Aniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.