Description

Fmoc-Ala-Ala-Pro-Oh is a high-purity, protected tripeptide building block used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring precise control over peptide sequence and structure. It is primarily utilized in pharmaceutical R&D for the development of therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the automated, sequential construction of longer, complex peptide chains.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics targeting various diseases.
• Bioconjugation & Probe Development: Serves as a component for creating labeled peptides used in diagnostic assays and biochemical studies.
• Combinatorial Chemistry Libraries: Employed to generate diverse peptide libraries for high-throughput screening against biological targets.
• Academic & Institutional Research: A fundamental reagent for studying peptide structure-activity relationships (SAR) and protein-protein interactions.
• Process Development: Used in scaling up and optimizing synthetic routes for peptide active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Fmoc-Ala-Ala-Pro-Oh
CAS No.	161220-53-7
Molecular Formula	C26H29N3O6
Molecular Weight	479.53 g/mol
Synonyms	Fmoc-Ala-Ala-Pro-OH; Fmoc-AAP-OH; N-(9-Fluorenylmethoxycarbonyl)-L-alanyl-L-alanyl-L-proline; (9H-Fluoren-9-yl)methyl (2S)-2-[[(2S)-2-[[(2S)-1-oxo-1-[(2S)-pyrrolidin-2-yl]propan-2-yl]amino]propanoyl]amino]propanoate; Fmoc-L-Ala-L-Ala-L-Pro-OH; Fmoc-AA(P)-OH; Fmoc-Ala-Ala-Pro; Fmoc-AAP
EINECS	Contact for details

Quality Control

Our Fmoc-Ala-Ala-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.