Description

(R)-(+)-Nadifloxacin CAS NO 160961-35-3 is the pure enantiomeric form of the broad-spectrum fluoroquinolone antibiotic nadifloxacin. This specific stereoisomer is of significant interest in advanced pharmaceutical research and development due to its targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel antibacterial agents and the study of structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of advanced antibacterial drugs.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate the efficacy of enantiomerically pure fluoroquinolones.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Mechanism of Action Studies: Facilitates research into the specific interactions between the (R)-enantiomer and bacterial DNA gyrase/topoisomerase IV enzymes.
• Process Chemistry Development: Used in the development and optimization of asymmetric synthesis routes for complex pharmaceutical molecules.

Basic Information

Product Name	(R)-(+)-Nadifloxacin
CAS No.	160961-35-3
Molecular Formula	C19H21FN2O4
Molecular Weight	360.38 g/mol
Synonyms	(+)-Nadifloxacin; (R)-Nadifloxacin; (R)-(+)-9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidyl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid; (R)-9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-6-carboxylic acid; (R)-OPC-7251; (R)-Acuatim; (R)-Fluxiderm
EINECS	Contact for details

Quality Control

Our (R)-(+)-Nadifloxacin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development purposes. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R)-enantiomer
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.