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L-Cysteine, D-Phenylalanyl-L-Cysteinyl-L-Phenylalanyl-D-Tryptophyl-L-Lysyl-L-Threonyl-, Cyclic (2→7)-Disulfide CAS NO 160841-00-9


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CAS No.:160841-00-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-Cysteine, D-Phenylalanyl-L-Cysteinyl-L-Phenylalanyl-D-Tryptophyl-L-Lysyl-L-Threonyl-, Cyclic (2→7)-Disulfide is a synthetic, cyclic heptapeptide derivative with a specific disulfide bridge between cysteine residues at positions 2 and 7. This complex molecular architecture is designed for high-affinity binding and potent biological activity, making it a critical intermediate for advanced pharmaceutical research and development. It is primarily utilized by biotechnology and pharmaceutical companies engaged in the discovery of novel peptide-based therapeutics, particularly in the fields of oncology, endocrinology, and metabolic disorders.

Application

  • Pharmaceutical Research & Development: Serves as a key intermediate or lead compound in the synthesis of novel peptide drugs targeting G-protein-coupled receptors (GPCRs).
  • Oncology Therapeutics: Investigated for its potential in developing targeted cancer therapies due to its specific receptor-binding properties.
  • Endocrine Disorder Treatment: Used in research for creating analogs to treat hormonal imbalances and metabolic diseases.
  • Bioconjugation & Drug Delivery: The defined cyclic structure and functional groups make it suitable for conjugation with other molecules to create advanced drug delivery systems.
  • Biochemical Research: Employed as a high-purity standard or reference material in analytical laboratories for method development and validation.
  • Preclinical Studies: Utilized in in vitro and in vivo studies to evaluate pharmacokinetics, efficacy, and safety profiles of new therapeutic candidates.

Basic Information

Item Details
Product Name L-Cysteine, D-Phenylalanyl-L-Cysteinyl-L-Phenylalanyl-D-Tryptophyl-L-Lysyl-L-Threonyl-, Cyclic (2→7)-Disulfide
CAS No. 160841-00-9
Molecular Formula C52H64N12O10S2
Molecular Weight 1081.27 g/mol
Synonyms Cyclo(-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-); c[D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys]; Somatostatin analog derivative; Cyclic heptapeptide disulfide; 160841-00-9; D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys (cyclic 2-7 disulfide); [Cyclic(2-7)]-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade and pharmaceutical intermediates. Every batch is characterized using advanced analytical techniques including HPLC, MS, and NMR to confirm identity, purity, and structural integrity. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are available upon request. We adhere to a cGMP-compliant quality management system where applicable to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed vial to warm to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Water Content (KF) ≤ 5.0%
Residual Solvents (GC) Meets ICH guidelines
Peptide Content ≥ 80.0% (by weight)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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