Description

Gatifloxacin Hydrochloride is a synthetic broad-spectrum fluoroquinolone antibiotic, specifically the hydrochloride salt form of gatifloxacin. This compound is a critical active pharmaceutical ingredient (API) valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of antibacterial medications, particularly for treating respiratory, urinary tract, and ocular infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of antibacterial drugs and ophthalmic solutions.
• Antibacterial Research: A key reference standard and intermediate in microbiological and pharmacological research for studying fluoroquinolone mechanisms.
• Veterinary Medicine: Used in the development of antibacterial treatments for veterinary applications.
• Analytical Standard: Serves as a high-purity standard for quality control and assay development in analytical laboratories.

Basic Information

Product Name	Gatifloxacin Hydrochloride
CAS No.	160738-57-8
Molecular Formula	C19H22FN3O4 • HCl
Molecular Weight	411.86 g/mol (Free base: 375.40)
Synonyms	Gatifloxacin HCl; (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid hydrochloride; AM-1155 hydrochloride; BMS-206584-01; Tequin (brand name derivative); Gatifloxacine Hydrochloride; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Gatifloxacin Hydrochloride is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Specifications typically align with pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.