Description

4-Chloro-6,8-Dimethylquinazoline is a versatile and high-purity quinazoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive chloro substituent and stable dimethylquinazoline core, enabling precise molecular construction for complex target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via cross-coupling reactions, nucleophilic substitutions, and metal-catalyzed transformations.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and corporate laboratories.

Basic Information

Product Name	4-Chloro-6,8-Dimethylquinazoline
CAS No.	160585-42-2
Molecular Formula	C10H9ClN2
Molecular Weight	192.64 g/mol
Synonyms	4-Chloro-6,8-dimethylquinazoline; 6,8-Dimethyl-4-chloroquinazoline; Quinazoline, 4-chloro-6,8-dimethyl-; 160585-42-2; 4-Chloro-6,8-dimethyl-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,8-Dimethylquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.