Description

D-Norleucine, 2-(Aminomethyl)- (9Ci) is a specialized, non-proteinogenic amino acid derivative characterized by its unique stereochemistry and functional groups. This compound is of significant value in advanced organic synthesis and pharmaceutical research, serving as a crucial chiral building block for the development of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in peptide mimetic design, medicinal chemistry, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in peptide-based therapeutics.
• Peptide Mimetics & Conformationally Restricted Analogs: Used to introduce structural constraints and novel side chains into peptide sequences to enhance stability, potency, and selectivity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Ligand Synthesis for Catalysis: Serves as a precursor for chiral ligands used in asymmetric synthesis and homogeneous catalysis.
• Proteomics & Chemical Biology: Utilized as a molecular probe or a tagged amino acid for studying protein-protein interactions and cellular processes.

Basic Information

Product Name	D-Norleucine, 2-(Aminomethyl)- (9Ci)
CAS No.	160557-06-2
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	D-2-(Aminomethyl)hexanoic acid; (R)-2-(Aminomethyl)hexanoic acid; D-2-Aminomethylcaproic acid; (2R)-2-(Aminomethyl)hexanoic acid; D-Homoleucine; D-2-Aminomethyl-n-hexanoic acid; D-α-(Aminomethyl)caproic acid
EINECS	Contact for details

Quality Control

Our D-Norleucine, 2-(Aminomethyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee product identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.