Description

H-L-Ile-L-Trp-Oh Tfa Salt is a high-purity, protected dipeptide building block used in advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over peptide sequence and structure for pharmaceutical and biochemical applications. It is primarily utilized in the development of therapeutic peptides, peptide hormones, and as a key intermediate in solid-phase peptide synthesis (SPPS) for the global life sciences industry.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex therapeutic peptides and peptide-based drug candidates.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid derivative in automated and manual peptide assembly.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies, receptor-ligand interaction assays, and metabolic pathway research.
• Peptide Library Construction: Employed in combinatorial chemistry for generating diverse peptide libraries for screening and discovery.
• API Development: An intermediate in the development and scale-up of Active Pharmaceutical Ingredients (APIs) with specific Ile-Trp sequences.
• Cosmeceutical Peptides: A potential ingredient in the research and development of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	H-L-Ile-L-Trp-Oh Tfa Salt
CAS No.	160448-56-6
Molecular Formula	C20H26N4O5 • C2HF3O2
Molecular Weight	526.47 g/mol (for TFA salt form)
Synonyms	H-Ile-Trp-OH TFA Salt; Isoleucyl-Tryptophan TFA Salt; L-Isoleucyl-L-tryptophan trifluoroacetate; Fmoc-Ile-Trp-OH (precursor); Boc-Ile-Trp-OH (precursor); Ile-Trp Dipeptide; N-(tert-Butoxycarbonyl)-L-isoleucyl-L-tryptophan; Z-Ile-Trp-OH
EINECS	Contact for details

Quality Control

Our H-L-Ile-L-Trp-Oh Tfa Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Total)	≥99.0%
Single Impurity (HPLC)	≤0.5%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.