Description

n-Biotinyl Glycine is a high-purity, synthetic biotin derivative where the biotin (vitamin B7) molecule is conjugated to a glycine amino acid via its valeric acid side chain. This specific molecular architecture makes it a crucial intermediate and building block for advanced biochemical research and pharmaceutical development. It is primarily utilized by R&D scientists and manufacturers in the life sciences sector for applications requiring precise biotinylation. The compound is supplied under stringent quality control to ensure batch-to-batch consistency for sensitive applications.

Application

• Bioconjugation & Probe Synthesis: Serves as a key precursor for creating biotin-labeled probes, tags, and linkers used in assay development.
• Pharmaceutical Intermediates: Used in the research and synthesis of novel drug candidates, particularly in targeted therapies and diagnostics.
• Biochemical Research Reagent: Essential for studying biotin-dependent processes, enzyme mechanisms, and protein interactions in vitro.
• Diagnostic Kit Manufacturing: Incorporated into the production of ELISA, lateral flow assays, and other diagnostic kits that utilize streptavidin-biotin technology.
• Peptide & Protein Modification: Enables site-specific biotinylation of peptides and proteins for purification (e.g., affinity chromatography) or detection purposes.
• Material Science & Surface Functionalization: Used to create biotinylated surfaces for biosensors, microarrays, and other biointerface applications.

Basic Information

Product Name	n-Biotinyl Glycine
CAS No.	160390-90-9
Molecular Formula	C12H21N3O4S
Molecular Weight	303.38 g/mol
Synonyms	Biotinylglycine; N-Biotinylglycine; Glycine, N-biotinyl-; Biotin-Gly-OH; (+)-Biotinylglycine; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(carboxymethyl)pentanamide; Vitamin H-Glycine conjugate
EINECS	Contact for details

Quality Control

Our n-Biotinyl Glycine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and pharmaceutical applications. Each batch is characterized by HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.