Description

Phl P I Allergen CAS NO 160227-82-7 is a highly purified, well-characterized reference standard for the major allergen from Timothy grass (*Phleum pratense*) pollen. This compound is critical for the research, development, and quality control of allergy diagnostics and immunotherapies. It is an essential reagent for scientists and manufacturers in the in-vitro diagnostic (IVD), pharmaceutical, and immunology research sectors.

Application

• Reference Standard for Immunoassays: Calibration and validation of ELISA, ImmunoCAP, and other serological tests for specific IgE detection.
• Allergen Component-Resolved Diagnostics (CRD): Enables precise identification of sensitization to the specific Timothy grass pollen allergen component.
• Vaccine & Immunotherapy Development: Serves as a key antigen in research for subcutaneous and sublingual allergy immunotherapy (AIT) formulations.
• Quality Control in IVD Manufacturing: Used as a critical raw material to ensure batch-to-batch consistency of allergy test kits.
• Biochemical & Immunological Research: Fundamental studies on allergen structure, IgE epitope mapping, and cross-reactivity patterns.
• Regulatory Compliance & Standardization: Supports method development and standardization efforts for regulatory submissions to agencies like the FDA and EMA.

Basic Information

Product Name	Phl P I Allergen
CAS No.	160227-82-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Phl p 1; Phleum pratense allergen Phl p 1; Timothy grass pollen allergen Phl p 1; Group 1 grass pollen allergen; Allergen Phl p I; Major Timothy grass pollen allergen; β-expansin allergen; Grass group I allergen.
EINECS	Contact for details

Quality Control

Our Phl P I Allergen is produced under stringent conditions to ensure high biological activity and purity, suitable for research and diagnostic applications. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and allergenicity. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), protein concentration, and immunological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Immunoblot/ELISA)	Positive reactivity with specific antibodies/IgE sera
Purity (SDS-PAGE)	≥ 90%
Purity (HPLC)	≥ 95%
Protein Content (BCA/Lowry)	≥ 90% of dry weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA/ImmunoCAP Inhibition)	Consistent with reference standard
Solubility	Soluble in aqueous buffers (PBS, etc.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.